- Agreement grants access to Synaffix patent portfolio related to metal-free click chemistry
- Technology to be used in Illumina’s next-generation sequencing (NGS) products
AMSTERDAM, THE NETHERLANDS, 4 December 2024 — Synaffix B.V., a Lonza company (SIX:LONN) focused on commercializing its clinical-stage bioconjugation platform technology for the development of antibody-drug conjugates (ADCs) with best-in-class therapeutic index and beyond, today announced it has entered into a licensing agreement with Illumina, Inc. (NASDAQ: ILMN), a global leader in DNA sequencing and array-based technologies. The agreement grants Illumina access to Synaffix’s patented metal-free click chemistry technology.
Synaffix’s patented metal-free click chemistry will be used in relation to certain Illumina next-generation sequencing (NGS) products.
Floris van Delft, Head of Research and Development at Synaffix, said: “At Synaffix, we are deploying a superior probe, bicyclononyne (BCN), for metal-free click chemistry for the highly selective generation of site-specific and stable antibody-drug conjugates for targeted treatment of cancer. There are also many other therapeutic applications and beyond, such as diagnostics and materials science, that can benefit from the unique chemical coupling properties of BCN. This transaction with Illumina serves as a testament to our ongoing commitment to deploy our innovative technologies in such new areas as we contribute towards making large-scale, whole-genome sequencing more accessible.”
