- Synaffix to provide Hummingbird Bioscience access to proprietary ADC technologies
- Synaffix to receive up to $150m in upfront and milestone payments plus royalties
Amsterdam and San Francisco / Houston / Singapore, 4 January 2023 — Synaffix B.V. (Synaffix), a biotechnology company focused on commercializing its clinical-stage platform technology for the development of antibody-drug conjugates (ADCs) with best-in-class therapeutic index, and Hummingbird Bioscience (Hummingbird Bio), a data-driven precision biotherapeutics company using its Rational Antibody Discovery (RAD) platform to discover and engineer antibodies against optimal yet elusive epitopes, thereby unlocking novel mechanisms of action, today announced that they entered into a licensing agreement that will enable Hummingbird Bio to develop a next generation ADC program using Synaffix technology.
Under the terms of the agreement, Synaffix will be eligible to receive up to $150 million, including upfront and milestone payments, plus royalties on net sales. For the target licensed, Hummingbird Bio is granted rights to utilize Synaffix proprietary ADC technologies GlycoConnect™ and HydraSpace™, in combination with select toxSYN™ linker-payloads.
Peter van de Sande, Chief Executive Officer of Synaffix, said: “We are pleased to once again be able to strengthen a partner’s pipeline with our innovative ADC technologies. By combining our cutting-edge ADC technology platform with Hummingbird Bio’s next-generation portfolio of precision therapeutics we can further contribute towards the transformation of cancer treatment.”
“Hummingbird Bio’s RAD platform generates high affinity antibodies against unique epitopes on hard targets, potentially unlocking novel mechanisms of action. We believe that, by combining Synaffix’s ADC technologies with our antibodies, we have the potential to create best-in-class ADCs.” said Piers Ingram, Ph.D., Chief Executive Officer and co-founder of Hummingbird Bio. “We are excited by the potential of this partnership and look forward to sharing additional updates on our ADC efforts throughout 2023.”
About Hummingbird Bioscience
Hummingbird Bioscience is a data-driven precision biotherapeutics company discovering and developing transformative biologic medicines for hard-to-treat diseases. The Hummingbird Bioscience model combines computational and systems biology with wet lab drug discovery in a multi-disciplinary, collaborative environment spanning initial discovery through clinical development. We harness this integrated approach across target identification and patient selection, enabling our team to increase the efficiency of translating novel scientific insights while reducing the inherent risk in drug discovery and development. We are currently developing two clinical-stage assets: HMBD-001, a humanized anti-HER3 monoclonal antibody targeting a novel epitope on HER3, and HMBD-002, a humanized anti-VISTA IgG4 monoclonal antibody. Both programs are currently in Phase 1 studies. At Hummingbird Bioscience, our commitment to rigorous science, teamwork and intellectual integrity underpins our passion to accelerate the journey of new drugs from concept to clinic.
Hummingbird Bioscience uses its proprietary Rational Antibody Discovery platform, to discover and engineer precision therapies against optimal yet elusive epitopes that have not been successfully drugged, unlocking novel mechanisms of action.
For more information, please visit www.hummingbirdbioscience.com, and follow Hummingbird Bioscience on LinkedIn, Twitter, and YouTube.
